TileEntity

Make a test without fusion

You can also make a test with a separate instance only using this mod If the issue is still there then it is definitely a mod issue - if not then maybe a conflict with another mod

Then I think it is some kind of bug with this mod - maybe try older builds

Same issue without JEI?

Hm I have no idea

Test it with allocating more RAM

Did you add NPCs via CustomNpcs? And is there a change with allocating more RAM?

Try other builds of Create

Make a test without nethersdelight

Make a test without modernfix, bobby and blueprint

Add logs with https://mclo.gs/

Some mods are conflicting with Create - like Ad Astra Maybe some mods require another Create build

Make a test with this build: https://www.curseforge.com/minecraft/mc-mods/supplementaries/files/6228530

Make a test without sound-physics

And without souls_like_bosses?

Same issue without lithostitched?

Downgrade Create Stuff and Addition to the previous build: https://www.curseforge.com/minecraft/mc-mods/create-stuff-additions/files/6168370

Delete the config of it (config folder)

Also add the latest.log (logs-folder)

Update your AMD/ATI drivers - get the drivers from their website - do not update via system

Same issue - I have no idea Maybe switch to a pre-configured modpack and use this as working base - then add new mods one by one

Does it work without chiselsandbits?

Same issue without the mod stonezone?

Add the latest.log (logs-folder) with sites like https://mclo.gs/ and paste the link to it here

Maybe a conflict between GeneticAnimals and Create